Cell Isolation – The Two Worlds of Cell Separation
Cell isolation, See REFERENCES below. An entertaining and useful explanation of the differences between the micro- and nano-particle techniques used for cell isolation / cell separation. Articles from RICE (mentioned in video): bit.ly bit.ly bit.ly bit.ly Article by Dr. Shenoy (mentioned in video): bit.ly Article on cellular responses to dextran-derivatised iron oxide nanoparticles: bit.ly Article on uptake of dextran-coated nanoparticles: bit.ly Article indicating induction of forced cellular iron elimination of nanoparticles: bit.ly Article on iron oxide nanoparticle toxicity: bit.ly Article on polystyrene nanosphere toxicity: bit.ly Article on nanoparticle impacts on gene expression: bit.ly Article on cell response to dextran-derivatised iron oxide nanoparticles post internalization: bit.ly Article on dextran derivatised iron oxide nanoparticles and their influence on fibroblasts: bit.ly Article on nanoparticle cytotoxicity and changes in cytokine induction: bit.ly Article on immunotoxicity of nanoparticles: bit.ly and bit.ly Article on metal oxide nanoparticle toxicity: bit.ly Article on receptor mediated endocytosis of nanoparticles: bit.ly From the fields of nanomedicine and nanotoxicology: bit.ly bit.ly bit.ly bit.ly bit.ly bit.ly Journal dedicated to nanotoxicology: informahealthcare.com More refs: en.wikipedia.org The European Commision’s initiative on the potential harmful effects of nanoparticles: bit.ly What level of uncertainty is acceptable? When searching …
Video Rating: 4 / 5
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22 Responses to “Cell Isolation – The Two Worlds of Cell Separation”
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Didn’t understand too :S
@TheSovietOverlord The illustration is good, i just don’t understand.
Why is this important?
i have no idea.. !!
i did not understand a thing i came here from terraria
@jlmknight Correct. Don’t you just love their work?!
is that the same hand that does RSAnimation?
@gdoitsh Glad you like it!
Capacity is not related to bead size. When you cover each cell with thousands of nanoparticles, you still need to use a column. The column contains big magnetic particles, amplifying the magnetic field by 10,000-fold to enable separation.
What the potential effect is of nanoparticles accumulating inside and/or on the cell surface is not yet fully understood.
Feel free to send us an email at ‘eurotech@lifetech.com’. Would love to discuss this in more detail
I am not convinced that microbeads create higher magnetic power. Many nanobeads can cover a single cell, providing an equal magnetic force. Also, because of their small size you can use them to isolate about 400 millions cells on one column.
In addition, resting cells (like blood lymphocytes) do not support endocytosis and therefore do not internalize the nanobeads (unless you pre activate them).
Overall that was a very informative presentation. Good job!
i have no idea what you’re talking about but this is pretty epic
@Llenhcs123 this looks just like the RSA animate series and I wish there were more of these videos for the medical sciences
very interesting, but a little over my head. I plan on re watching multiple times to gain full understanding.
Highly uniform == neckties. I almost fell off my chair laughing.
Fantastic artwork but “therapuetic”
wow how did this come up as I’m studying this tonight
This is so AMAZINGLY done!!! Terrific job.
Hello, I would like to develop a similar kind of video for my business, would you mind sharing the agency you used?
Thanks
You Rock guys
@Llenhcs123
This was totally awesome!!! GREAT JOB!!
Very creative, well done.
yep k got it buy cornflakes.